Publication highlight: Jasper Williams
PSPG student Jasper Williams publishes in Cell
Roybal, K.T., Williams, J.Z., Morsut, L., Rupp, L.J., Kolinko, I., Choe, J.H., Walker, W.J., McNally, K.A., Lim, W.A. (2016) Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 167, 419-432 See article
Summary: SynNotch T cells drive customized therapeutic responses for cancer and other diseases. SynNotch T cells can be engineered to sense tumor antigens and locally deliver biologics such as antibodies, and can thus be used as a smart platform for local delivery of diverse therapeutic payloads capable of remodeling microenvironments.