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Publication highlight: Jasper Williams

PSPG student Jasper Williams publishes in Cell

Roybal, K.T., Williams, J.Z., Morsut, L., Rupp, L.J., Kolinko, I., Choe, J.H., Walker, W.J., McNally, K.A., Lim, W.A. (2016) Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 167, 419-432 See article

Summary:  SynNotch T cells drive customized therapeutic responses for cancer and other diseases.  SynNotch T cells can be engineered to sense tumor antigens and locally deliver biologics such as antibodies, and can thus be used as a smart platform for local delivery of diverse therapeutic payloads capable of remodeling microenvironments.


 

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