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Publication highlight: Jasper Williams

PSPG student Jasper Williams publishes in Cell

Roybal, K.T., Williams, J.Z., Morsut, L., Rupp, L.J., Kolinko, I., Choe, J.H., Walker, W.J., McNally, K.A., Lim, W.A. (2016) Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors. Cell. 167, 419-432 See article

Summary:  SynNotch T cells drive customized therapeutic responses for cancer and other diseases.  SynNotch T cells can be engineered to sense tumor antigens and locally deliver biologics such as antibodies, and can thus be used as a smart platform for local delivery of diverse therapeutic payloads capable of remodeling microenvironments.


BBC Faculty to head up new NSF funded Bioengineering Center

BBC Faculty to head up new NSF funded Bioengineering Center:

NSF Funds ‘Blue Sky’ Bioengineering Center To Be Based at UCSF

Center Aims to Unite Bay Area Synthetic Biologists, Engineer Biological Machines

The National Science Foundation has awarded $24 million over five years for a new ‘blue-sky’ bioengineering center based at UC San Francisco. Known as the Center for Cellular Construction, the new initiative aims to transform the field of cell biology into a quantitative discipline and to adapt tools from engineering, the physical sciences, and computer science to design automated machines out of living cells.  

Our PUBS course students published a paper!

Yeast in a class of their own: Our graduate students report how genetics and chemical stresses interact to affect the fitness of yeast cells. Read more: https://medium.com/lifes-building-blocks/yeast-in-a-class-of-their-own-4...

International team of researchers including faculty member Brian Shoichet develop safer opioid painkiller from scratch

Researchers including faculty member Brian Shoichet develop safer opioid painkiller from scratch:

An international team of researchers — led by scientists at UC San Francisco, Stanford University, the University of North Carolina, and the Friedrich-Alexander University Erlangen-Nürnberg in Germany — has developed a new opioid drug candidate that blocks pain without triggering the dangerous side effects of current prescription painkillers. Read more:  http://www.universityofcalifornia.edu/news/researchers-develop-safer-opi...

Dr. Les Benet presents the commencement address and wins the 2016 Outstanding Mentor Award

PSPG faculty member Dr. Les Benet presented the 2016 commencement address and was also the recipient of the 2016 Outstanding Mentor Award conferred by the Associated Students of the Graduate Division Alumni Association: http://graduate.ucsf.edu/commencement-celebration-2016

PSPG alum Max Seibold appointed Director of the NJH new Program in Regenerative Medicine and Genome Editing (REGEN)

Congratulations PSPG Alumni Max Seibold!  The NJH Office of Academic Affairs and the Center for Genes, Environment and Health has announce the creation of a Program in Regenerative Medicine and Genome Editing (REGEN) to be directed by Max A. Seibold, Ph.D.  The overall mission of the program will be to advance regenerative medicine approaches for understanding the etiology of, and advance potential therapies for, lung and immunological diseases.  Initially, the REGEN program will focus on the establishment of stem cell techniques, including induced pluripotent stem cell (iPSC) derivation and experimentation at National Jewish Health.  A main emphasis of the program will also be on the modification of disease genes and genetic variants in iPSCs for disease modeling and therapy.  Dr. Seibold will name Assistant Directors for the program and engage the broader NJH community in seminars regarding the program this fall.

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