drug discovery and development

New computer models were able to successfully predict negative side effects for hundreds of currently marketed drugs, report researchers from the UCSF School of Pharmacy, SeaChange Pharmaceuticals, and Novartis Institutes for Biomedical Research in a paper published online this week in the journal...

Michael Fischbach, PhD, who studies drug-like molecules produced by human gut bacteria, has been awarded one the 16 prestigious 2011 Packard Fellowships in Science and Engineering.

The fellowship, which supports “highly creative professors early in their careers,” provides an unrestricted research...

Pharmaceutical companies will increasingly apply the predictive modeling of quantitative pharmacology to do more efficient drug development, says Kathy Giacomini, PhD, co-chair of the Department of Bioengineering and Therapeutic Sciences (BTS), a joint department of the UCSF Schools of Pharmacy and...

The new UCSF Center for Quantitative Pharmacology housed within the Department of Bioengineering and Therapeutic Sciences (BTS), a joint department of the Schools of Pharmacy and Medicine, will be inaugurated next week with a wide-ranging, 2-day conference, September 22 and 23, 2011 at William J. ...

The bacteria in the human gut that produce antibiotics are the focus of a US$1 million W. M. Keck Foundation grant being led by Michael Fischbach, PhD, a faculty member in the UCSF School of Pharmacy.

Michael Fischbach, PhD, is the recipient of a 2010 NIH Director’s New Innovator Award from the National Institutes of Health. Fischbach is a faculty member in the Department of Bioengineering and Therapeutic Sciences, UCSF Schools of Pharmacy and Medicine.

Through study results of a particular enzyme of unknown function, called Tm0936, that is found in a bacterium that lives in thermal vents in the Mediterranean Ocean, UCSF School of Pharmacy faculty member Brian Shoichet, PhD and colleagues are shedding light on how to ultimately better predict the...

James A. Wells, PhD, an internationally recognized biochemist and leader in the development of new technologies for engineering proteins and for identifying small molecules to aid drug discovery, has been named chair of the Department of Pharmaceutical Chemistry in the UCSF School of Pharmacy. His...

The odds of finding a chemical compound that can be developed into a drug are not good, says Thomas James, PhD, chair of the UCSF School of Pharmacy's department of pharmaceutical chemistry, but those odds can be improved by university scientists.

UCSF School of Pharmacy faculty member James Wells, PhD, director of the Small Molecule Discovery Center, describes his approach, which uses precise, sophisticated matchmaking techniques, to improving the success rate of finding chemical compounds with the potential to become drugs.

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